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Piribedil loaded thermo-responsive nasal in situ gelling system for enhanced delivery to the brain: formulation optimization, physical characterization, and in vitro and in vivo evaluation
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[oai_citation:4PubMed]( [oai_citation:5PMC]( 4) Growth-hormone receptor (GHR) expression in tendon fibroblasts Gene-expression and protein studies found dose- and time-dependent up-regulation of GHR
The net binding enthalpies are predicted from molecular dynamics simulations that capture the complex Coulomb sum of short- and long-range electrostatic interactions in the receptor binding pocket [52, 53]
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