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EMA Decision P/0336/2024 Paediatric Investigation Plan for Retatrutide
While the GLP-1 class has dominated the conversation, cagrilintide targets the amylin system, a separate hormonal pathway that influences hunger, satiety, and digestion in its own way
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Buse, M.D., from the University of North Carolina School of Medicine in Chapel Hill, and colleagues randomly assigned 2,713 adults with inadequately controlled type 2 diabetes receiving metformin with or without SGLT2i with overweight or obesity to receive cagrilintide-semaglutide, semaglutide, cagrilintide, or placebo for 68 weeks
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