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Enzymes essential for glycolysis, the TCA cycle, and the ETC are oxidized in the AD brain, leading to decreased activity
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Consistent with the in vitro results above, transfer of Lip-1 ex vivotreated 2C CD8 + T cells significantly inhibited tumor growth in B16-SIYbearing mice (Supplemental Figure 2, AC) accompanied by an increased accumulation and effector function of transferred CD8 + T cells within tumors (Supplemental Figure 2, DH)
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