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This is because extra fat tissue produces an enzyme (aromatase) that turns testosterone into estrogen, which can leave men with lower testosterone
however, aspirin is not currently prescribed for cancer prophylaxis owing to its adverse effects such as the risk of bleeding
Some prescribers move patients up the dose ladder too quickly, often to get to the dose thats supposed to work. This usually causes side effects severe enough that the patient either stops the medication or has to drop back down
10.1111/cen.13003 Clin Endocrinol (Oxf)
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