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For patients with significant weight to lose, especially 60 pounds or more, surgical results tend to be more durable over a 5 to 10 year window than medication-only approaches, largely because the anatomical change doesnt disappear when you stop a prescription
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Semaglutide and tirzepatide are GLP-1 receptor agonists, meaning they mimic the hormone glucagon-like peptide-1 (GLP-1), which plays a crucial role in regulating blood sugar, digestion, and appetite
doi: 10.1016/j.numecd.2019.07.012
van Dijk G, Thiele TE
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