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Topiramate adds appetite suppression through GABA modulation and is also beneficial for patients with concurrent migraine

A pre-mixed aqueous product began degrading from the moment of reconstitution at the vendor's facility

Allergan is also conducting a 48-week Phase 2b TANDEM study (ClinicalTrials.gov NCT03517540) in collaboration with Novartis AG to evaluate the safety and efficacy of a combination of Tropifexor, a FXR agonist, and CVC in 200 patients with biopsy-proven NASH with fibrosis (CRN stage 2 or 3) (Figure 2)