Glutathione S-transferases (GSTs) are involved in cell protection, antioxidation and detoxification of toxic and foreign compounds within the cell by conjugating them to glutathione
more specifically, exposure to 10 and 20 mg/kg fluoxetine reduced the body and testicular weights in offspring, decreased spermatogonial tubule and epithelial volumes, altered the seminiferous tubule length and the number of supporting cells, and increased the number of seminiferous tubules lacking a lumen
If these levels remain chronically low, it can contribute to the development or worsening of various disease states, including: (3, 4) Premature aging (and aging in general) Neurodegenerative disorders Cancer Cognitive impairment Diabetes HIV/AIDS Autoimmunity Infertility Mental health disorders Hypertension Fatty liver disease That doesnt cover the full spectrum, but it gives you a pretty good idea of how important glutathione is
After a two-week period of supplement administration, a significant increase in erythrocyte GSH levels was observed in the treated (TRT) group, nearly reaching the physiological threshold by the end of the study