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Concentrations typically used in cell culture range from 10 ng/mL for sensitive signaling assays to 100 ng/mL for full receptor saturation studies

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JMF4073 eliminates WT-Bcr-Abl-transformed myeloid cells in vitro and in vivo Since the balanced supply of dNTPs is critical for overcoming DNA damage and replication stress for cell survival, we then tested whether JMF4073 treatment could selectively suppress the growth of Bcr-Abl-transformed but not untransformed myeloid cells

Cross-contamination from peptide vials