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doi: 10.1111/bph.70145
These findings invite further exploration into the broader behavioral and metabolic applications of GLP-1 RAs beyond diabetes and obesity, especially in psychiatric and preventive care settings
Obesity, as a global chronic disease characterized by excessive fat accumulation, affects the health of approximately 650 million people and is associated with an increased risk of multiple metabolic complications, such as Type 2 diabetes and non-alcoholic fatty liver disease, as well as cardiovascular diseases and mechanical issues, including osteoarthritis and obstructive sleep apnea
GCGR adopts an elongated conformation whereas GLP-1R adopts a tilted or closed conformation
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