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This test may help provide context for why a patient responds robustly to one medication versus another, or why side effects vary

The First Four to Eight Weeks During the initial phase, patients may notice: Less hunger between meals Earlier fullness Fewer cravings Reduced interest in large or high-fat meals Improved ability to follow a structured eating plan Weight loss may be modest during this period because patients are still receiving introductory doses

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After centrifugation at 16,000 g for 15 min at 4 C, the supernatant was transferred to new tubes