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Stand on a step with heels hanging off the edge Rise up on toes using both legs Shift weight to affected leg only Slowly lower heel below step level over 3 to 5 seconds Return to starting position using both legs Perform 15 repetitions, 3 sets, twice daily Expect some discomfort during exercise

While anecdotal evidence exists, rigorous clinical trials are lacking

Rapid clearance means that even a significant excess dose is substantially eliminated within 3 to 4 hours, limiting the window of any pharmacologic effect

Vitamins B1, B6, and B12 are water-soluble, and as such, when absorbed into the body, they are excreted via the kidneys