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Consequently, many GSH-responsive nanoplatforms are designed either to deplete GSH by targeting these pathways or to exploit high GSH levels as triggers for selective drug release
Most common side effects are nausea, vomiting, stomach upset, diarrhea, tiredness, dizziness, or constipation
Importantly, as shown in the first row, LASSS supplementation effectively prevented an increase in the nitration level of ECM-HGF, whereas GSSSG did not demonstrate efficacy, inconsistent with its potent potential shown in in vitro experiments described earlier (see Figure 1b)
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