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GLP-1 therapies have been effective in the treatment of type 2 diabetes and more recently, as a treatment of obesity to reduce appetite
Human participants were generally overweight, obese, or insulin-resistant adults, while animal studies predominantly employed diet-induced obese or genetically modified rodent models
However, there are some more serious potential risks associated with GLP-1 RAs, including semaglutide
It stimulates the pituitary gland to release growth hormone, which plays a significant role in regulating growth, metabolism, and tissue repair
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