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Histologically, it is characterized by in situ increased production of melanin by basal melanocytes, which are otherwise normal in number and distribution (13), or display increased numbers of melanocytes along the junctional zone in the case of the labial melanotic macules (14)
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A study involving 70 patients with acne compared a 20% azelaic acid cream plus a 15% glycolic acid lotion to a 0.025% tretinoin solution, applied twice daily for 12 weeks
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