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The FDA labels for semaglutide products note that mean increases in resting heart rate of 1-4 beats per minute have been observed, with some patients experiencing larger increases

Management of acute liver failure in the intensive care unit setting

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Contact your healthcare provider within 24 hours for: Recurrent episodes of right upper abdominal pain, even if they resolve Persistent indigestion or bloating that is new or worsening Changes in stool color (pale or clay-colored) or dark urine Unexplained nausea that differs from typical semaglutide side effects Any abdominal pain that concerns you or interferes with daily activities Your provider may order diagnostic tests including abdominal ultrasound (the first-line imaging for gallstones), liver function tests, complete blood count, and lipase levels if pancreatitis is suspected