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XJZ showed the strongest effect, followed by XJZ-C (XJZ without complement drug) and XJZ-A (XJZ without assistant drug), and XJZ-P (XJZ without principal drug) the least
A conservative, well-researched dose is likely to produce a minimal, perhaps even unnoticeable, effect on blood pressure
The case report literature on GLP-1 agonists and anorgasmia identifies decreased norepinephrine signaling as a potential contributor to orgasmic dysfunction, which represents a separate but related concern from decreased desire
Patients reported that side-effects persisted during the semaglutide dose escalation, after which the symptoms subsided in all, but were still present at the time of discontinuation of semaglutide (timepoint 2)
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