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This finding was refuted by Borden, who reiterated that the only reliable prognostic indicator is the stage of the disease at diagnosis and not pregnancy

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Western blot analysis was utilized to measure the expression of GLP-1R, PKA/CREB pathway components and inflammation-related proteins, such as tumor necrosis factor-alpha (TNF-), interleukin-1 beta (IL-1), and IL-6

Thus, weight loss not only reduces mechanical pressure but also decreases inflammatory factors