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There is insufficient safety data for either compound during pregnancy, and animal studies with GLP-1 agonists showed adverse fetal effects
It is commonly referenced in research settings as a ghrelin receptor/growth hormone secretagogue receptor-related compound
EMBO J [Internet]
Individuals who are pregnant, planning on becoming pregnant, or breastfeeding, have a history of severe kidney or liver disease, pancreatitis, gallbladder disease, diabetic retinopathy, thyroid C-cell tumors, or certain types of cancer, or those who have had severe hypersensitivity to semaglutide or any of its components may not be suitable for this treatment
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