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Shahmiri M, Enciso M, Adda CG, Smith BJ, Perugini MA, Mechler A
Experimental studies in animal models indicate that IL-1 acts upstream of other proinflammatory cytokines, as the administration of an IL-1 receptor antagonist not only attenuates neurodegeneration but also significantly reduces TNF- and IFN- protein levels in the mesencephalon [195]
Understanding these potential effects helps patients make informed decisions about their supplementation regimen and recognise when symptoms warrant medical attention
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