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A post-hoc analysis of SURMOUNT-5 estimated a larger reduction in predicted 10-year cardiovascular risk with tirzepatide (23.7%) than semaglutide (13.6%), but these are modeled projections, not measured outcomes

More than 100 peptide drugs are currently FDA-approved in the U.S

Role in the body: It has been linked to the regulation of sleep cycles, modulation of stress hormones like cortisol, and even influence over pituitary hormone release (such as LH and GH)