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estradiol patches after Bayer discontinued Climara in 2023), the FDAs removal of boxed warnings on HRT products (which accelerated prescribing), and tariff pressures on overseas pharmaceutical manufacturing
Clinical studies on FDA-approved GLP-1 medications have shown meaningful weight-loss outcomes when combined with healthy lifestyle changes, including reductions of up to 14.9% in body weight
And the gastrointestinal side effects of semaglutide, particularly nausea and acid reflux, can make restful sleep difficult
Later dose decisions depend on a consistent monitoring baseline
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