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The medication's effect on gastric emptying can lead to feelings of fullness, bloating, and discomfort, which may be difficult to distinguish from IBS symptoms
Tirzepatide for managing overweight and obesity Technology Appraisal TA1026
Although Glp1r mRNA transcripts are detected in whole heart extracts such methods do not distinguish between vascular smooth muscle cells or atrial cardiomyocytes, there were technical difficulties in isolating pure cardiomyocyte populations from the ventricle without contamination of atrial cardiomyocytes isolated from neonatal mouse [36]
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