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Severe, persistent abdominal pain (with or without vomiting), signs of gallstones (right upper abdominal pain, jaundice), or signs of dehydration warrant urgent medical assessment

DOI: Published online: February 14, 2024 1 Borthwick Diabetes Research Centre, Lister Hospital, Stevenage, UK 2 Diabetes Complications Research Centre, University College Dublin, Dublin, Ireland Corresponding author: Adie Viljoen

This is the most common complaint in patient surveys about GLP-1 access (Luo et al., JAMA Network Open 2024)

Indeed Shibao and coauthors demonstrated that after ganglionic blockade with trimethaphan, hypertensive obese patients exhibited a greater BP fall than the normotensive ones (Shibao et al., 2007)