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Handlers are advised to consult the relevant literature on both compounds to determine potential interactions [13]
(2) the specific CI inhibitor IACS-010759 was recently reported to promote neurotoxicity, making this an unattractive agent for combination therapy in CRC given the neurotoxicity long-recognized with oxaliplatin treatment 51
While peptides are generally less immunogenic than larger proteins, they can still trigger antibody formation in some patients
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