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[7] That preclinical promise carried the compound into a human Phase II program for postoperative ileus but the randomized, placebo-controlled trial in bowel-resection patients did not meet its primary efficacy endpoint, and clinical development was subsequently discontinued

GLP-1 receptor agonists in PD Approved treatments for PD target dopaminergic neurotransmission, with levodopa representing the mainstay of treatments augmenting dopamine production and alleviating motor symptoms [6]

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