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Based on the establishment and development of the theory of the pathological roles of free radicals, the role of GPxs has gradually attracted researchers attention, and the involvement of GPxs in the occurrence and development of malignant tumors has been shown

Acknowledgements The authors acknowledge the support of Faculty of Pharmacy, Sri Adichunchanagiri College of Pharmacy and Adichunchanagiri University for providing the necessary facilities to carry out this work

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