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Additionally, we found that weight loss was greater for patients without type 2 diabetes than for those with evidence of type 2 diabetes, though differences in effectiveness between tirzepatide and semaglutide were similar
PMC 2634690
The main mechanisms with research support: Collagen and connective tissue: GHK-Cu upregulates collagen synthesis and metalloproteinases the enzymes that remodel old, damaged collagen
They are also believed to increase leptin sensitivity, as determined by decreased leptin levels in non-diabetic women with obesity who lost weight on exenatide
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