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Diagnosis typically involves blood tests including full blood count (showing macrocytosis), anti-intrinsic factor antibodies (which are specific for pernicious anaemia), and sometimes anti-parietal cell antibodies
It's frequently referenced alongside MOTS-c and NAD+ in research contexts, given the complementary nature of their respective pathway interactions - particularly how NNMT inhibition influences NAD+ availability in metabolic signalling studies
Injections avoid the need for gastrointestinal absorption and may be the appropriate route for specific persistent causes or higher-risk presentations
The symptoms are more common at the start of treatment
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