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This is a mechanism no approved drug currently uses Phase 2 trials showed up to 24% body weight reduction over 48 weeks, meaningfully exceeding tirzepatide and semaglutide outcomes Phase 3 trials are currently underway
The strong safety profile reflects that both peptides are based on naturally occurring compounds
This is a natural biological response, not a sign of drug dependence
For example, injecting tirzepatide right after exercise or in hot weather can increase local blood flow and make the site look redder or more swollen
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