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En los estudios PIONEER, semaglutida oral 14mg mostr una reduccin de HbA1c de 1,20% en comparacin con liraglutida 1,80mg (1,10%) en el estudio PIONEER-431 y de 1,70% en comparacin con dulaglutida 0,75mg (1,40%) en el estudio PIONEER-1032
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A 2021 clinical trial reported that over 12 weeks, patients taking semaglutide orally lost an average of 5.95 pounds
Before its development, all other GLP-1 drugs were only available as injections
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