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In aging, when melatonin output diminishes, this synchronization is weakened contributing to internal desynchrony and various functional impairments ( To summarize melatonins roles relevant to aging, Table 1 provides an overview of some key functions of melatonin and how they change or impact physiology in older adults

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Its structure promotes prolonged activity, allowing researchers to investigate mechanisms related to protein synthesis , muscle cell proliferation , and metabolic efficiency