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Adding a second mechanism (phentermines norepinephrine pathway) can break through the plateau in selected patients

Dietary modifications are often the first-line approach to managing stomach problems on Wegovy: Eat smaller, more frequent meals rather than large portions, as this reduces gastric distension and works with the delayed gastric emptying caused by semaglutide Avoid high-fat, greasy, or spicy foods , which can exacerbate nausea and slow digestion further Stay well hydrated , sipping water throughout the day, but avoid drinking large volumes with meals Limit alcohol and caffeine , both of which can irritate the gastric mucosa Avoid lying down immediately after eating

The impact of the initial doses may include some gastrointestinal side effects, such as nausea and diarrhea

As some data on the continuous covariates were missing, single expectationmaximization imputation was performed before conducting propensity score matching