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Choline is involved in early development of the brain, gene expression, cell membrane signaling, and brain metabolism

This regularity helps maintain optimal vitamin B12 levels in the body, ensuring continuous support for various bodily functions that rely on this essential nutrient

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In the Phase 2 trial, participants who started directly at 4 mg (without the 2 mg titration period) experienced nearly double the rate of gastrointestinal adverse events compared to those who started at 2 mg (Jastreboff et al., NEJM 2023)