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Following GLP-1 RA therapy, patients' reduced inflammation and improved insulin sensitivity may enhance responsiveness to these generic medications

Adherence is another major issue one study suggested that roughly two-thirds of patients discontinue GLP-1 therapy within the first year, often due to high costs, gastrointestinal side effects, lack of perceived benefit, or difficulty maintaining lifestyle changes

Kras mutations increase telomerase activity and targeting telomerase is a promising therapeutic strategy for Kras-mutant NSCLC

GLP-1 RAs mimic naturally occurring GLP-1, an enterohormone produced in response to oral intake that regulates glucose metabolism and promotes weight loss