Keywords: Glutathione, topical, antioxidant, pigmentary disorders, skin bleaching Introduction Glutathione, a low molecular weight thiol-tripeptide, is renowned for its potent antioxidant properties and has recently garnered attention for its potential skin-lightening effects, raising significant ethical debates regarding its use
Hypotension: Low blood pressure, often related to dehydration or concomitant antihypertensive medications requiring adjustment as weight decreases
In Phase 2/3 clinical trials, participants lost an average of 24-29% of body weight at the highest doses (8-12 mg) over 48-68 weeks
Obvious vacuoles, very small amounts of sperm, a small number of early spermatogenic cells, extremely disordered cell arrangement, reduced cell layer number, the disappearance of cell polarity and a reduced Johnsen score were observed