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Available from: Accessed 7 Jul 2023 Fras JP, Davies MJ, Rosenstock J et al (2021) Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes
In addition, combined inhibition of Wnt, Notch, and epidermal growth factor receptor (EGFR) pathways, as well as combined inhibition of Wnt, Notch, and mitogen-associated protein kinase (MAPK), increase differentiation of Lgr5 + stem cells towards EECs and abolished differentiation of goblet cells and Paneth cells in intestinal Organoids [199] (Fig
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