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It has been shown that in patients with type 2 diabetes mellitus (T2DM) the response to the incretin effect is altered as a result of a severe defect in the sensitivity for GIP in the cells [4] and a reduction in food-induced GLP-1 secretion [5, 6]
The additional weight loss with bupropion/naltrexone was 4% to 5%
Landmark trials showed robust weight loss with both semaglutide and tirzepatide
Popular diabetes drug may also reduce the risk of severe liver disease
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