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The generation of these ROS within the phagocytic complexes of macrophages and neutrophils is the means by which these cells degrade phagocytosed microorganisms

That plate of hot wings or fast food binge might be tempting, but they can also slow down digestion or further upset an already uneasy stomach

30 We build on this work to develop three complementary formulation design strategies to engineer long-acting peptide depots: (i) hydrogel vehicle formulation to tune micellar crosslink density and bulk mechanical properties, (ii) cargo complexation to modulate intermolecular interactions and effective diffusion within the matrix, and (iii) oxidation-prevention strategies such as sacrificial antioxidant excipients to protect sensitive residues and stabilize the peptide during residence in the depot

PMID: 40162642