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For example, in chronic granulomatous disease with fungal infections, the Dectin-1 C-type lectin receptor, which recognizes -glucans, and TLRs mediate cytokine responses in wild-type murine neutrophils through the activation of tyrosine phosphatase PTPN11-SYK and downstream caspase recruitment domain family member 9 (CARD9)-dependent NF-B as well as CARD9-independent JNK-c-Jun pathways
Ingredients Chicken Meal, Cracked Pearled Barley, Pea Fiber, Whole Grain Wheat, Whole Grain Corn, Corn Gluten Meal, Whole Grain Sorghum, Powdered Cellulose, Chicken Liver Flavor, Soybean Oil, Dried Beet Pulp, Flaxseed, Lactic Acid, Pork Flavor, Potassium Chloride, L-Lysine, Iodized Salt, Choline Chloride, Calcium Carbonate, vitamins (Vitamin E Supplement, L-Ascorbyl-2-Polyphosphate (source of Vitamin C), Niacin Supplement, Thiamine Mononitrate, Vitamin A Supplement, Calcium Pantothenate, Riboflavin Supplement, Biotin, Vitamin B12 Supplement, Pyridoxine Hydrochloride, Folic Acid, Vitamin D3 Supplement), minerals (Ferrous Sulfate, Zinc Oxide, Copper Sulfate, Manganous Oxide, Calcium Iodate, Sodium Selenite), Taurine, Oat Fiber, Mixed Tocopherols for freshness, L-Carnitine, Natural Flavors, Beta-Carotene, Apples, Broccoli, Carrots, Cranberries, Green Peas
Symptoms can range from mild occasional muscle cramping to severe weakness or even death
