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The molecular basis for this selectivity difference is not fully characterized at the structural level but is attributed to ipamorelin's distinct binding mode at the receptor's orthosteric site, which appears to bias the downstream signaling cascade toward the GH-releasing pathway rather than the full spectrum of ghrelin receptor activity

m6A reader YTHDC2 mediates NCOA4 mRNA stability affecting ferritinophagy to alleviate secondary injury after intracerebral haemorrhage