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Any references to insulin-like growth factor, growth-related pathways, or metabolic endpoints are provided for scientific context only
The second is dose and route translation : even where an effect is real in a mouse, the human-equivalent dose is not a simple body-weight scaling, and as the route section above stressed there is no human bioavailability figure to anchor an oral-versus-injected comparison
Elevated serum B12 levels discovered incidentally on blood tests are often asymptomatic
A significant factor is often the substantial caloric restriction that accompanies treatment
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