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The STEP 4 withdrawal trial demonstrated that discontinuation of semaglutide 2.4 mg after a 20-week run-in is followed by nearly complete weight regain within one year an outcome that is more accurately framed as disease recurrence in a chronic relapsing condition than as drug failure (Quimbayo-Cifuentes, 2026)
10.1007/s00380-018-01327-4 123
Benefits: Gives Radiant and Smooth Skin
However, Novo was soon hit by higher-than-expected demand, as well as supply issues, that prompted the drugmaker to put marketing on hold as of March
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