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PubMed 4.Prkacin I et al
In the Yale study, the most commonly reported issues were nausea, diarrhea, vomiting, and constipation
Regarding lipids metabolism, multiple studies have confirmed its close correlation with epilepsy: for example, sphingosine 1-phosphate can protect mitochondrial structure and function to alleviate neuronal hyperexcitability and damage in patients with DRE (143)
These isoenzymes are reported to be singly or multi-expressed in a variety of normal tissues, including stomach, bowel, brain, heart, liver, pancreas, breast, kidney and skin at differing levels
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