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Doses of pyridoxine as low as 5-10 mg can antagonize levodopas effect if carbidopa is not present, so caution is warranted and any supplemental B beyond the nutritional dose should be under medical guidance
Fix: Pick a protocol, stick with it consistently for the full duration, then assess results
To support this metabolic process, some clinicians recommend co-supplementation with a methyl donor such as trimethylglycine (TMG) while on NAD+ injections
This route of administration is particularly useful in patients who find it difficult to take B12 in liquid and tablet forms
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