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Preliminary observational data and case reports have suggested that some patients with both obesity and lymphedema experience symptomatic improvement when treated with GLP-1 agonists for weight management

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These are cell-biology observations and they do not translate directly to human outcomes

27 In addition, p53 still promotes the activation of several genes that are not part of the extrinsic or intrinsic apoptotic pathways, and these genes may regulate the response of cells to death-inducing factors