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OR, odds ratio
Metformin, by regulating the Loc100506691-miR-26a-5p-miR-330-5p-CHAC1 axis, induces cell cycle arrest in the G2/M phase, inhibiting cancer cell proliferation (71)
What the clinical evidence shows Several large, peer-reviewed studies have quantified the risk: The STEP 1 trial (NEJM, 2021): patients on high-dose semaglutide lost an average of 14.9% of their body weight over 68 weeks
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