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Immunologically, in Hurley Stage II, the persistent action of pro-inflammatory M1 CD68 + macrophages impedes wound healing and drive the prolonged chronic inflammation [72] in which CD163 macrophages with M2-like features emerge, implicated in ECM deposition and fibrotic remodeling [76, 77]
Reduces Inflammation and Oxidative Stress GHK-Cu helps calm inflammatory signaling and reduce oxidative damagetwo major drivers of aging and slow recovery
Journal of Sleep Research, 5(3), 150- 154
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