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Patients with a history of depression, anxiety disorders, bipolar disorder, or previous suicidal thoughts warrant closer monitoring during GLP-1 treatment, as these pre-existing conditions represent the most significant risk factors for suicidal ideation
Adding up to 200 mM of strong Cu(II) chelators (DTPA, EDTA) at pH 7.4 did not decrease the metal content in CuCP peak even after 100 min incubation with 200 mM EDTA or 21 h incubation with 100 mM DTPA (Supplementary Information, Figure S1a)
16 Risk of nutrient deficiencies: GLP-1 agonists significantly reduce appetite, gastrointestinal motility, and nutrient absorption, leading to reduced calorie and protein intake
Engage in regular physical activity, which stimulates intestinal motility
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