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The biggest mistake I see is stopping the protocol as soon as symptoms improve
It makes the hard work of lifestyle change easier and more effective
Women also tend to have lower baseline creatine stores than men, which means they may benefit disproportionately from supplementation
Second, the patient should meet established criteria for pharmacologic weight management intervention, such as BMI 30 kg/m or BMI 27 kg/m with weight-related comorbidities, consistent with FDA indications
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