The AES (Supplementary Note 1) were obtained using the BAC-knockouts as templates for a PCR using primers described in (Supplementary Table 2)
declares having received consulting honoraria from Amgen, Boehringer Ingelheim, Merck, Pfizer, Aegerion, Novartis, Sanofi, Takeda, Novo Nordisk and Bayer, and research grants from British Heart Foundation, MRC (UK), NIHR, PHE, MSD, Pfizer, Aegerion, Colgate and Roche
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